Hematology

 

Dr. Lerche KG – Leading Reference Measurement Laboratory in Hematology

Dr. Lerche KG is one of the leading reference measurement laboratories in Germany, specializing in the determination of reference method values in interlaboratory comparisons for the Complete Blood Count (CBC). These comparisons serve as part of the external quality assurance for hematological laboratories and are organized on behalf of the German Medical Association by the Reference Institute for Bioanalytics (RfB) and the Society for the Promotion of Quality Assurance in Medical Laboratories (INSTAND e.V.).

Our Measurement Methods – Precision in Hematological Analysis

We provide highly accurate determinations of:

Erythrocyte concentration according to DIN 58932-3:2024-02
Leukocyte concentration according to DIN 58932-4:2003-07
Hemoglobin concentration according to DIN 58931:2010-08

State-of-the-Art Technology for Maximum Accuracy

Erythrocyte and Leukocyte Concentration Measurement

The determination of cell concentration is conducted through the gravimetric preparation of measurement solutions from control blood, followed by precise measurement using a Coulter Counter.

The Coulter Counter operates based on electrical impedance measurement:

  • An electrically conductive solution separates two electrodes.
  • When a cell passes through the capillary, the electrical resistance changes.
  • Each change generates an electrical pulse, which is used to count the cells.

This method allows for high-precision, automated cell counting.

Hemoglobin Concentration Measurement

Hemoglobin analysis is performed via photometric measurements at a wavelength of 540 nm, based on the Lambert-Beer law:

A = ε * c * d

  • A = Measured absorption
  • ε = Molar extinction coefficient of hemoglobin
  • c = Substance concentration
  • d = Cuvette path length

By measuring light absorption, we determine the precise hemoglobin concentration in the control blood sample.

Our Services – External Quality Control for Your Laboratory

Benefit from our expertise to enhance the accuracy of your blood analysis devices and quality control for control blood samples:

  • Comparison of your measurement results with our reference values
  • Analysis of your samples based on customized specifications
  • Detailed reports for comprehensive quality assurance

Why Choose Dr. Lerche KG?

Specialized in hematological reference measurements
Extensive experience in interlaboratory comparisons
Highest precision using state-of-the-art analytical technology
Customized consultation and detailed reports

Contact us today and optimize the quality of your laboratory analyses with Dr. Lerche KG – Your expert laboratory for precise reference measurements!

 

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